Published by on June 16, 2026 Leukemia, by Dr. Lalita Norasetthada, Hematology Unit, Department of Internal Medicine, Faculty of Medicine, Chiang Mai University. Leukemia is caused by an abnormality of the hematopoietic stem cells in the bone marrow, resulting in an abnormal, massive, and uncontrolled proliferation of white blood cells in the bone marrow. This leads to the accumulation of white blood cells until the bone marrow is full, after which they are released into the bloodstream, causing an abnormally high number of white blood cells in the blood. Leukemia is divided into two main groups according to disease progression: acute leukemia, a disease characterized by the proliferation of immature white blood cells that cannot mature into normal white blood cells, resulting in a rapid increase of immature white blood cells in the bone marrow and a consequent decrease in the production of all types of blood cells. […]