{"id":308,"date":"2026-06-16T22:18:39","date_gmt":"2026-06-16T15:18:39","guid":{"rendered":"https:\/\/dnacenter.thaizone.net\/%e0%b8%81%e0%b8%b2%e0%b8%a3%e0%b8%ab%e0%b8%b2%e0%b8%a2%e0%b9%84%e0%b8%9b%e0%b8%82%e0%b8%ad%e0%b8%87-y-chromosome-%e0%b8%81%e0%b8%b1%e0%b8%9a%e0%b8%84%e0%b8%a7%e0%b8%b2%e0%b8%a1%e0%b9%80%e0%b8%aa\/"},"modified":"2026-06-16T22:18:39","modified_gmt":"2026-06-16T15:18:39","slug":"%e0%b8%81%e0%b8%b2%e0%b8%a3%e0%b8%ab%e0%b8%b2%e0%b8%a2%e0%b9%84%e0%b8%9b%e0%b8%82%e0%b8%ad%e0%b8%87-y-chromosome-%e0%b8%81%e0%b8%b1%e0%b8%9a%e0%b8%84%e0%b8%a7%e0%b8%b2%e0%b8%a1%e0%b9%80%e0%b8%aa","status":"publish","type":"post","link":"https:\/\/dnacenter.thaizone.net\/en\/%e0%b8%81%e0%b8%b2%e0%b8%a3%e0%b8%ab%e0%b8%b2%e0%b8%a2%e0%b9%84%e0%b8%9b%e0%b8%82%e0%b8%ad%e0%b8%87-y-chromosome-%e0%b8%81%e0%b8%b1%e0%b8%9a%e0%b8%84%e0%b8%a7%e0%b8%b2%e0%b8%a1%e0%b9%80%e0%b8%aa\/","title":{"rendered":"Loss of the Y chromosome and the risk of cancer in males"},"content":{"rendered":"<p>&nbsp;<\/p>\n<h1 class=\"story-body__h1\" style=\"color: rgb(30, 30, 30); font-variant-numeric: inherit; font-stretch: inherit; font-family: Helmet, Freesans, Helvetica, Arial, sans-serif; font-size: 2rem; font-weight: bold; line-height: 1.125; margin-bottom: 0px; padding-top: 0px; padding-bottom: 0px; vertical-align: baseline;\">Y chromosome linked to cancer and death risk in men<\/h1>\n<div class=\"byline\" style=\"color: rgb(64, 64, 64); font-variant-numeric: inherit; font-stretch: inherit; font-family: Helmet, Freesans, Helvetica, Arial, sans-serif; font-size: 14px; line-height: inherit; margin-top: 16px; vertical-align: baseline;\">\n<figure class=\"media-landscape has-caption full-width lead\" style=\"color: inherit; font-style: inherit; font-variant: inherit; font-stretch: inherit; font-family: inherit; font-weight: inherit; letter-spacing: inherit; line-height: inherit; margin-top: 32px; margin-right: -54.2188px; vertical-align: baseline; background-color: rgb(17, 17, 17); clear: both;\"><span class=\"image-and-copyright-container\" style=\"color: inherit; font-style: inherit; font-variant: inherit; font-stretch: inherit; font-family: inherit; font-weight: inherit; letter-spacing: inherit; line-height: inherit; vertical-align: baseline; display: block; position: relative;\"><img decoding=\"async\" class=\"js-image-replace\" alt=\"Old man\" src=\"https:\/\/ichef.bbci.co.uk\/news\/660\/media\/images\/78434000\/jpg\/_78434021_m2450971-depression-spl.jpg\" data-highest-encountered-width=\"660\" style=\"border-width: 0px; border-style: initial; color: rgb(189, 189, 189); font-style: inherit; font-variant: inherit; font-stretch: inherit; font-family: inherit; font-weight: inherit; letter-spacing: inherit; line-height: inherit; vertical-align: baseline; height: auto; max-width: 100%; user-select: none; width: 645.781px; display: block;\" \/><span class=\"off-screen\" style=\"color: inherit; font-style: inherit; font-variant: inherit; font-stretch: inherit; font-family: inherit; font-weight: inherit; letter-spacing: inherit; line-height: inherit; vertical-align: baseline; clip: rect(1px 1px 1px 1px); overflow: hidden; position: absolute !important; height: 1px !important; width: 1px !important;\">Image copyright<\/span><span class=\"story-image-copyright\" style=\"color: rgb(236, 236, 236); font-style: inherit; font-variant: inherit; font-stretch: inherit; font-family: inherit; font-size: 0.75rem; font-weight: inherit; letter-spacing: 0.25px; line-height: 1.33333; padding: 3px 8px 1px; vertical-align: baseline; text-transform: uppercase; background: rgba(0, 0, 0, 0.6); bottom: 0px; position: absolute; right: 0px;\">SPL<\/span><\/span><figcaption class=\"media-caption\" style=\"color: inherit; font-style: inherit; font-variant: inherit; font-stretch: inherit; font-family: inherit; font-weight: inherit; letter-spacing: inherit; line-height: inherit; padding: 16px; vertical-align: baseline; visibility: visible;\"><span class=\"off-screen\" style=\"color: inherit; font-style: inherit; font-variant: inherit; font-stretch: inherit; font-family: inherit; font-weight: inherit; letter-spacing: inherit; line-height: inherit; vertical-align: baseline; clip: rect(1px 1px 1px 1px); overflow: hidden; position: absolute !important; height: 1px !important; width: 1px !important;\">Image caption<\/span><span class=\"media-caption__text\" style=\"color: rgb(236, 236, 236); font-style: inherit; font-variant: inherit; font-stretch: inherit; font-family: inherit; font-size: 0.8125rem; font-weight: inherit; letter-spacing: inherit; line-height: 1.23077; vertical-align: baseline; display: block;\">The study looked at blood tests in more than 1,000 men aged over 70 for Y chromosome loss<\/span><\/figcaption><\/figure>\n<p class=\"story-body__introduction\" style=\"font-style: inherit; font-variant: inherit; font-stretch: inherit; font-family: inherit; font-size: 1rem; font-weight: bold; letter-spacing: inherit; line-height: 1.375; margin-top: 28px; vertical-align: baseline;\">The male Y chromosome may have a role in prolonging men&#8217;s lives and fighting cancer, scientists have said.<\/p>\n<p style=\"font-style: inherit; font-variant: inherit; font-stretch: inherit; font-family: inherit; font-size: 1rem; font-weight: inherit; letter-spacing: inherit; line-height: 1.375; margin-top: 23px; vertical-align: baseline;\">Research into 1,153 elderly men at the University of Sweden found those who had lost part of their Y chromosome died on average 5.5 years earlier than those who had not.<\/p>\n<p style=\"font-style: inherit; font-variant: inherit; font-stretch: inherit; font-family: inherit; font-size: 1rem; font-weight: inherit; letter-spacing: inherit; line-height: 1.375; margin-top: 18px; vertical-align: baseline;\">Women live on average 7.5 years longer than men in Europe and the reasons behind this are not fully known.<\/p>\n<p style=\"font-style: inherit; font-variant: inherit; font-stretch: inherit; font-family: inherit; font-size: 1rem; font-weight: inherit; letter-spacing: inherit; line-height: 1.375; margin-top: 18px; vertical-align: baseline;\">Cancer Research said the study was &quot;intriguing&quot;.<\/p>\n<p style=\"font-style: inherit; font-variant: inherit; font-stretch: inherit; font-family: inherit; font-size: 1rem; font-weight: inherit; letter-spacing: inherit; line-height: 1.375; margin-top: 18px; vertical-align: baseline;\">Scientists assessed how many blood cells had age-related loss of the Y chromosome (LOY) through blood tests in the men, aged between 70 and 84.<\/p>\n<h2 class=\"story-body__crosshead\" style=\"color: rgb(30, 30, 30); font-style: inherit; font-variant: inherit; font-stretch: inherit; font-family: inherit; font-size: 1.25rem; font-weight: inherit; letter-spacing: inherit; line-height: 1.2; margin-top: 18px; padding-top: 0px; padding-bottom: 0px; vertical-align: baseline;\">Tumour prevention<\/h2>\n<p style=\"font-style: inherit; font-variant: inherit; font-stretch: inherit; font-family: inherit; font-size: 1rem; font-weight: inherit; letter-spacing: inherit; line-height: 1.375; margin-top: 18px; vertical-align: baseline;\">Men with a &quot;significant amount&quot; of loss died earlier, said researchers. LOY was associated with general risk of death in 637 out of the group of men and risk of death due to non-blood related cancer in 132 of the cases.<\/p>\n<aside class=\"quote\" style=\"color: inherit; font-style: inherit; font-variant: inherit; font-stretch: inherit; font-family: inherit; font-size: 0.9375rem; letter-spacing: 0px; line-height: 1.334; margin-top: 18px; margin-bottom: 24px; margin-left: 16px; padding-top: 0.0625rem; padding-bottom: 0.1875rem; vertical-align: baseline; float: right; clear: both; width: 197.172px;\">\n<div class=\"quote-inner\" style=\"border-top: 8px solid rgb(220, 220, 220); color: inherit; font-style: inherit; font-variant: inherit; font-stretch: inherit; font-family: inherit; font-weight: inherit; letter-spacing: inherit; line-height: inherit; padding-top: 8px; vertical-align: baseline; overflow: hidden; position: relative;\">\n<blockquote class=\"quote\" style=\"color: inherit; font-style: inherit; font-variant: inherit; font-stretch: inherit; font-family: inherit; font-size: 1rem; font-weight: 700; letter-spacing: 0px; line-height: 20px; padding-top: 0.0625rem; padding-bottom: 0.1875rem; vertical-align: baseline; quotes: none;\"><p>While a man&#8217;s risk of cancer does increase with age, there are things all men can do to stack the odds in their favour<\/p>\n<footer style=\"color: gray; font-style: inherit; font-variant: inherit; font-stretch: inherit; font-family: inherit; font-size: 0.875rem; font-weight: 300; letter-spacing: 0px; line-height: 1.33; padding-top: 0.0625rem; padding-bottom: 0.1875rem; vertical-align: baseline;\">Dr Julie Sharp, Cancer Research<\/footer>\n<\/blockquote>\n<\/div>\n<\/aside>\n<p style=\"font-style: inherit; font-variant: inherit; font-stretch: inherit; font-family: inherit; font-size: 1rem; font-weight: inherit; letter-spacing: inherit; line-height: 1.375; margin-top: 18px; vertical-align: baseline;\">Researchers said the association between LOY and early death was significant when the results were adjusted for age and other health conditions.<\/p>\n<p style=\"font-style: inherit; font-variant: inherit; font-stretch: inherit; font-family: inherit; font-size: 1rem; font-weight: inherit; letter-spacing: inherit; line-height: 1.375; margin-top: 18px; vertical-align: baseline;\">Women don&#8217;t have the Y chromosome, but have two Xs instead.<\/p>\n<p style=\"font-style: inherit; font-variant: inherit; font-stretch: inherit; font-family: inherit; font-size: 1rem; font-weight: inherit; letter-spacing: inherit; line-height: 1.375; margin-top: 18px; vertical-align: baseline;\">The co author of the study, Jan Dumanski from Uppsala University in Sweden, said: &quot;Many people think the Y chromosome only contains genes involved in sex determination and sperm production.<\/p>\n<p style=\"font-style: inherit; font-variant: inherit; font-stretch: inherit; font-family: inherit; font-size: 1rem; font-weight: inherit; letter-spacing: inherit; line-height: 1.375; margin-top: 18px; vertical-align: baseline;\">&quot;In fact, these genes have other important functions, such as possibly playing a role in preventing tumours.&quot;<\/p>\n<p style=\"font-style: inherit; font-variant: inherit; font-stretch: inherit; font-family: inherit; font-size: 1rem; font-weight: inherit; letter-spacing: inherit; line-height: 1.375; margin-top: 18px; vertical-align: baseline;\">The study said Y chromosome genes were not expressed when LOY occurred, meaning its potential role in tumour prevention could be reduced.<\/p>\n<h2 class=\"story-body__crosshead\" style=\"color: rgb(30, 30, 30); font-style: inherit; font-variant: inherit; font-stretch: inherit; font-family: inherit; font-size: 1.25rem; font-weight: inherit; letter-spacing: inherit; line-height: 1.2; margin-top: 18px; padding-top: 0px; padding-bottom: 0px; vertical-align: baseline;\">Immune system<\/h2>\n<p style=\"font-style: inherit; font-variant: inherit; font-stretch: inherit; font-family: inherit; font-size: 1rem; font-weight: inherit; letter-spacing: inherit; line-height: 1.375; margin-top: 18px; vertical-align: baseline;\">It said LOY in blood cells was associated with many different cancers, including those outside the blood system.<\/p>\n<p style=\"font-style: inherit; font-variant: inherit; font-stretch: inherit; font-family: inherit; font-size: 1rem; font-weight: inherit; letter-spacing: inherit; line-height: 1.375; margin-top: 18px; vertical-align: baseline;\">Researchers said this could be because Y chromosome genes enabled blood cells to help with immuno-surveillance, where the immune system detected and killed tumour cells to prevent cancer.<\/p>\n<p style=\"font-style: inherit; font-variant: inherit; font-stretch: inherit; font-family: inherit; font-size: 1rem; font-weight: inherit; letter-spacing: inherit; line-height: 1.375; margin-top: 18px; vertical-align: baseline;\">The finding means blood tests looking at the state of the Y chromosome could help predict a man&#8217;s risk of cancer, say the authors.<\/p>\n<p style=\"font-style: inherit; font-variant: inherit; font-stretch: inherit; font-family: inherit; font-size: 1rem; font-weight: inherit; letter-spacing: inherit; line-height: 1.375; margin-top: 18px; vertical-align: baseline;\">Head of health information at Cancer Research Dr Julie Sharp said: &quot;This is an intriguing theory but more research is needed to establish whether loss of the Y chromosome really could be a predictor of cancer risk.<\/p>\n<p style=\"font-style: inherit; font-variant: inherit; font-stretch: inherit; font-family: inherit; font-size: 1rem; font-weight: inherit; letter-spacing: inherit; line-height: 1.375; margin-top: 18px; vertical-align: baseline;\">&quot;While a man&#8217;s risk of cancer does increase with age, there are things all men can do to stack the odds in their favour, such as not smoking, maintaining a healthy weight, eating healthily and cutting down on alcohol.&quot;<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>&nbsp; Y chromosome linked to cancer and death risk in men Image copyrightSPLImage captionThe study looked at blood tests in more than 1,000 men aged over<span class=\"excerpt-hellip\"> [\u2026]<\/span><\/p>\n","protected":false},"author":0,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[5],"tags":[],"class_list":["post-308","post","type-post","status-publish","format-standard","hentry","category-5"],"_links":{"self":[{"href":"https:\/\/dnacenter.thaizone.net\/en\/wp-json\/wp\/v2\/posts\/308","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/dnacenter.thaizone.net\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/dnacenter.thaizone.net\/en\/wp-json\/wp\/v2\/types\/post"}],"replies":[{"embeddable":true,"href":"https:\/\/dnacenter.thaizone.net\/en\/wp-json\/wp\/v2\/comments?post=308"}],"version-history":[{"count":0,"href":"https:\/\/dnacenter.thaizone.net\/en\/wp-json\/wp\/v2\/posts\/308\/revisions"}],"wp:attachment":[{"href":"https:\/\/dnacenter.thaizone.net\/en\/wp-json\/wp\/v2\/media?parent=308"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/dnacenter.thaizone.net\/en\/wp-json\/wp\/v2\/categories?post=308"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/dnacenter.thaizone.net\/en\/wp-json\/wp\/v2\/tags?post=308"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}